BDBM50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine
SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
InChI Key InChIKey=QZUDBNBUXVUHMW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 150 hits for monomerid = 50001884
Affinity DataKi: 6.87nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2 short form expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Competitive binding affinity against human Dopamine receptor D2S by displacing [3H]spiperone from CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Ability of the compound to displace [3H]-spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells ...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity of compound was tested in vitro for its ability to compete with [3H]spiperone radioligand at cloned human Dopamine receptor D2L stab...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity against dopamine receptor D2S using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:In vitro binding affinity for Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compoundMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Ability of the compound to displace [3H]-spiperone from the cloned human Dopamine receptor D2L stably expressed in Chinese hamster ovary (CHO) cells ...More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2L stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Binding affinity to human D2R assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]SCH23390 from human cloned dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Binding affinity against dopamine receptor D2L using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Binding affinity against dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity was determined against Dopamine receptor D2 using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity was determined against Dopamine receptor D2 using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Displacement of [3H]-raclopride from human D2LR expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Binding affinity to human dopamine D2L receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Binding affinity towards cloned human Dopamine receptor D2 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D2 stably expressed in CHO cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity against Dopamine receptor D2 from rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity towards dopamine D2 receptors in rat brain synaptosomal preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity of [3H]-YM-09151 towards cloned mammalian Dopamine receptor D2 expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Displacement of [3H]spiperone from wild-type human dopamine D2S receptor expressed in CHO-K1 cell membrane after 2 hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 89.1nMAssay Description:Displacement of [3H]spiperone from wild-type human dopamine D2S receptor expressed in CHO-K1 cell membrane after 2 hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Ability to displace [3H]-spiperone from human cloned Dopamine receptor D2 expressed in CHO K-1 cells in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Binding affinity against cloned human dopamine receptor D2 expressed in Chinese hamster ovary (CHO) K-1 cells by displacement of [3H]-spiperone.More data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Binding affinity measured at the Dopamine receptor D2 by the inhibition of [3H]-methylspiperone binding to rat striatum using unlabeled haloperidol f...More data for this Ligand-Target Pair